Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24894886 | 1.00 | LRRK2 (0.34) | LRRK2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL30141576 | 0.94 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL29197189 | 0.94 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL25473799 | 0.94 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL24894908 | 0.86 | MAPT (0.32) | HRH3 | |
| SCHEMBL12731410 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL19867589 | 0.78 | MAPT (0.43) | HRH3 | |
| SCHEMBL24894999 | 0.78 | LRRK2 (0.35) | LRRK2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL31153309 | 0.78 | LRRK2 (0.35) | LRRK2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL29197145 | 0.78 | LRRK2 (0.35) | LRRK2CHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940435-A | Novel compounds for diagnosing TDP-43 proteinopathies | AC免疫有限公司 | 2024-04-26 | — | — | CN | disclosed |