Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24894908 | 0.89 | MAPT (0.32) | MAPTHRH3KCNH2GPR119 | |
| SCHEMBL12731410 | 0.85 | MAPT (0.36) | MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29197189 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL30141576 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL25473799 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL12731668 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31372447 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10137346 | 0.83 | HRH4 (0.40) | ALDH1A1HRH3ALOX15 | |
| SCHEMBL9946217 | 0.80 | MAPT (0.51) | MAPTARTSHRALDH1A1NPC1 | |
| SCHEMBL24894886 | 0.78 | LRRK2 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066447-B2 | Aureobasidium derivatives and methods of synthesis | AueroGen Biosciences, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20190292225-A1 | AUREOBASIDIUM DERIVATIVES AND METHODS OF SYNTHESIS | AUREOGEN BIOSCIENCES, INC. | 2019-09-26 | — | — | US | disclosed |
| WO-2018031521-A1 | AUREOBASIDIUM DERIVATIVES AND METHODS OF SYNTHESIS | AUREOGEN BIOSCIENCES, INC. (US) | 2018-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292225-A1 | AUREOBASIDIUM DERIVATIVES AND METHODS OF SYNTHESIS | ERG28, FDPS, AAAS | MAPT 2044/4885AR 1044/4885TSHR 4413/4885 |
| US-11066447-B2 | Aureobasidium derivatives and methods of synthesis | ERG28, FDPS, AAAS | MAPT 2044/4885AR 1044/4885TSHR 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.