Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | ME2 | P23368 | 3/20 | 0.38 |
| ▸ | ME1 | P48163 | 3/20 | 0.38 |
| ▸ | ME3 | Q16798 | 3/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112454 | 1.00 | GPR119 (0.40) | GPR119NTRK1ALDH1A1MAPTRET | |
| SCHEMBL31382516 | 0.90 | MAPT (0.41) | GPR119ALDH1A1MAPT | |
| SCHEMBL25199235 | 0.88 | GPR119 (0.53) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL30888790 | 0.88 | GPR119 (0.53) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL30888783 | 0.86 | CKS1B (0.42) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL24670866 | 0.86 | CKS1B (0.42) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL25074365 | 0.84 | RET (0.40) | GPR119ALDH1A1MAPTRETCKS1B | |
| SCHEMBL29197698 | 0.82 | AAK1 (0.43) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL30112336 | 0.82 | AAK1 (0.43) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL25504062 | 0.82 | CNR2 (0.44) | NTRK1ALDH1A1ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |