Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 4/20 | 0.43 |
| ▸ | SKP1 | P63208 | 4/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112569 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1GAACTSLCTSB | |
| SCHEMBL25504062 | 0.83 | CNR2 (0.44) | ALDH1A1CNR1CNR2 | |
| SCHEMBL30112428 | 0.82 | DGAT1 (0.43) | ALDH1A1CKS1BSKP1SKP2TSHR | |
| SCHEMBL29197741 | 0.82 | DGAT1 (0.43) | ALDH1A1CKS1BSKP1SKP2TSHR | |
| SCHEMBL23459570 | 0.82 | PRMT5 (0.41) | KCNH2 | |
| SCHEMBL29872807 | 0.82 | PRMT5 (0.41) | KCNH2 | |
| SCHEMBL30981240 | 0.82 | CHRM4 (0.52) | EPHX1ALDH1A1GAACTSLCTSB | |
| SCHEMBL30981116 | 0.82 | CHRM4 (0.44) | EPHX1ALDH1A1GAACTSLCTSB | |
| SCHEMBL30981348 | 0.82 | CTSL (0.42) | EPHX1ALDH1A1GAACTSLCTSB | |
| SCHEMBL31306744 | 0.81 | PDE10A (0.40) | ALDH1A1TSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |