Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | KLK7 | P49862 | 9/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901678 | 0.89 | TSHR (0.81) | TSHRKLK7TDP1SMN1; SMN2KMT2A | |
| SCHEMBL13893698 | 0.86 | KLK7 (0.61) | KLK7TDP1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL9478302 | 0.85 | KLK7 (0.59) | KLK7TDP1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL17230514 | 0.83 | SMN1; SMN2 (0.61) | KLK7TDP1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL7525162 | 0.83 | ALDH1A1 (0.64) | TDP1SMN1; SMN2L3MBTL1ALDH1A1CYP2C19 | |
| SCHEMBL7639014 | 0.83 | HTT (0.53) | KLK7TDP1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL9626909 | 0.81 | TSHR (0.70) | TSHRKLK7TDP1KMT2A | |
| SCHEMBL5175026 | 0.81 | TSHR (0.76) | TSHRKLK7HTTALDH1A1KMT2A | |
| SCHEMBL10309729 | 0.81 | TSHR (0.70) | TSHRKLK7TDP1L3MBTL1KMT2A | |
| SCHEMBL14010060 | 0.81 | TSHR (0.70) | TSHRKLK7TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348517-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2023-11-02 | — | — | US | disclosed |
| US-11643429-B2 | Compounds and methods for the treatment of ocular disorders | Azura Ophthalmics Ltd. (IL) | 2023-05-09 | — | — | US | disclosed |
| US-20210230205-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2021-07-29 | — | — | US | disclosed |
| EP-2003104-B1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | JITSUBO CO LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-8293948-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8293948-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8293948-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | JITSUBO CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | JITSUBO CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | JITSUBO CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-8093435-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8093435-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8093435-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-2003104-A9 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-2003104-A2 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230205-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | SERPINB1, KLKB1, MPO | TSHR 2435/4885KLK7 52/4885TDP1 1989/4885 |
| US-11643429-B2 | Compounds and methods for the treatment of ocular disorders | SERPINB1, KLKB1, MPO | TSHR 2435/4885KLK7 52/4885TDP1 1989/4885 |
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | COASY, OSTC, OGA | TSHR 2440/4885KLK7 1282/4885TDP1 3716/4885 |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | COASY, OSTC, OGA | TSHR 2440/4885KLK7 1282/4885TDP1 3716/4885 |
| US-20230348517-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | SERPINB1, KLKB1, MPO | TSHR 2435/4885KLK7 52/4885TDP1 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.