Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 17/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036941 | 0.84 | NOTUM (0.50) | ACKR3KCNH2 | |
| SCHEMBL20536341 | 0.78 | NOTUM (0.47) | TP53 | |
| SCHEMBL2032761 | 0.75 | ACKR3 (0.46) | ACKR3KCNH2TP53 | |
| SCHEMBL8375031 | 0.75 | ACKR3 (0.47) | ACKR3KCNH2 | |
| SCHEMBL19814410 | 0.73 | HSD17B1 (0.33) | — | |
| SCHEMBL29775767 | 0.73 | HSD17B1 (0.33) | — | |
| SCHEMBL29775813 | 0.71 | ACKR3 (0.56) | ACKR3KCNH2 | |
| SCHEMBL11902510 | 0.71 | ACKR3 (0.56) | ACKR3KCNH2 | |
| SCHEMBL28331160 | 0.71 | ACKR3 (0.44) | ACKR3KCNH2PIK3CG | |
| SCHEMBL24726444 | 0.70 | ACKR3 (0.55) | ACKR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417334-A | Azole derivative containing isoxazole structure, and preparation method and application thereof | 沈阳药科大学 | 2024-01-19 | — | — | CN | disclosed |