SCHEMBL29775813

SCHEMBL29775813

O=C(O)c1cc(-c2ccc(F)cc2F)on1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACKR3 P25106 11/20 0.56
KMO O15229 2/20 0.54
ALDH1A1 P00352 3/20 0.51
KCNH2 Q12809 1/20 0.50
PTPRB P23467 1/20 0.49
PTPN1 P18031 2/20 0.49
BRD4 O60885 1/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11902510 1.00 ACKR3 (0.56) ACKR3KMOALDH1A1KCNH2PTPRB
Hydrochloric Acid SCHEMBL29141689 0.98 ACKR3 (0.55) ACKR3KMOALDH1A1KCNH2PTPRB
SCHEMBL24726444 0.86 ACKR3 (0.55) ACKR3KMOALDH1A1KCNH2MEN1
SCHEMBL29939026 0.86 ACKR3 (0.55) ACKR3ALDH1A1KCNH2MEN1NPC1
SCHEMBL29775719 0.84 KMO (0.56) ACKR3KMOALDH1A1PTPN1BRD4
SCHEMBL11903309 0.84 KMO (0.56) ACKR3KMOALDH1A1PTPN1BRD4
SCHEMBL29775731 0.84 ALDH1A1 (0.50) ACKR3ALDH1A1PTPRBPTPN1BRD4
SCHEMBL19815128 0.84 ALDH1A1 (0.50) ACKR3ALDH1A1PTPRBPTPN1BRD4
SCHEMBL70022 0.82 ALDH1A1 (0.62) ACKR3ALDH1A1PTPN1BRD4MEN1
SCHEMBL19245763 0.82 ACKR3 (0.61) ACKR3ALDH1A1KCNH2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727359-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-04-22 EP disclosed
EP-4626882-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-08 EP disclosed
WO-2025104152-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-05-22 WO disclosed
WO-2024256433-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-12-19 WO disclosed
CN-119060036-A ATF6 inhibitors and uses thereof 阿尔托斯实验室公司 2024-12-03 CN disclosed
CN-118955415-A Continuous synthesis method of 5- (2, 4-difluorophenyl) isoxazole-3-ethyl formate 深圳智微通科技有限公司 2024-11-15 CN disclosed
CN-118894779-A Method for continuously synthesizing ethyl 4- (2, 4-difluorophenyl) -2, 4-dioxobutyrate 深圳智微通科技有限公司 2024-11-05 CN disclosed
EP-4448534-A1 MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES Syngenta Crop Protection AG (CH) 2024-10-23 EP disclosed
EP-4447682-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-10-23 EP disclosed
CN-112313224-B ATF6 inhibitors and uses thereof 阿尔托斯实验室公司 2024-08-13 CN disclosed
EP-4346411-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-04-10 EP disclosed
CN-117769551-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2024-03-26 CN disclosed
CN-117396073-A Microbiocidal tetrahydroisoquinoline derivatives 先正达农作物保护股份公司 2024-01-12 CN disclosed
CN-111683945-B Crystalline forms of CXCR7 receptor antagonists 爱杜西亚药品有限公司 2023-11-10 CN disclosed
WO-2023110871-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023110869-A1 MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023012044-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed
WO-2022253645-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 WO disclosed
CN-109563085-B Piperidine CXCR7 receptor modulators 爱杜西亚药品有限公司 2022-08-09 CN disclosed
CN-110563717-B Piperidine CXCR7 receptor modulators 爱杜西亚药品有限公司 2022-08-09 CN disclosed