Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870533 | 1.00 | POLB (0.44) | POLBGRM4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29198166 | 1.00 | POLB (0.44) | POLBGRM4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30870598 | 0.90 | GRM4 (0.40) | POLBGRM4ALDH1A1KMT2AMEN1 | |
| SCHEMBL29198165 | 0.90 | GRM4 (0.40) | POLBGRM4ALDH1A1KMT2AMEN1 | |
| SCHEMBL30870626 | 0.89 | POLB (0.45) | POLBGRM4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28502106 | 0.89 | POLB (0.45) | POLBGRM4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28512461 | 0.85 | MAPT (0.49) | POLBALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30870559 | 0.85 | MAPT (0.49) | POLBALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29198258 | 0.85 | POLB (0.43) | POLBGRM4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29198178 | 0.85 | EGFR (0.43) | POLBGRM4KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |