Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870547 | 1.00 | EGFR (0.43) | EGFRROS1ALKGRM4POLB | |
| SCHEMBL28502106 | 0.85 | POLB (0.45) | GRM4POLBLMNAMAPK1HTT | |
| SCHEMBL30870626 | 0.85 | POLB (0.45) | GRM4POLBLMNAMAPK1HTT | |
| SCHEMBL29198168 | 0.85 | POLB (0.44) | GRM4POLBLMNAMAPK1HTT | |
| SCHEMBL29198166 | 0.85 | POLB (0.44) | GRM4POLBLMNAMAPK1HTT | |
| SCHEMBL30870533 | 0.85 | POLB (0.44) | GRM4POLBLMNAMAPK1HTT | |
| SCHEMBL29198258 | 0.84 | POLB (0.43) | EGFRROS1ALKGRM4POLB | |
| SCHEMBL28512461 | 0.82 | MAPT (0.49) | POLBMALT1LMNAHTTKDM4E | |
| SCHEMBL30870559 | 0.82 | MAPT (0.49) | POLBMALT1LMNAHTTKDM4E | |
| SCHEMBL30870543 | 0.82 | POLB (0.40) | EGFRROS1ALKGRM4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |