Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29198240 | 0.96 | MALT1 (0.41) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL30870559 | 0.89 | MAPT (0.49) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL28512461 | 0.89 | MAPT (0.49) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL30870552 | 0.84 | MCHR1 (0.42) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL28905772 | 0.84 | MCHR1 (0.42) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL29198163 | 0.82 | PTPN2 (0.43) | MAPTHTTALDH1A1LMNAKDM4E | |
| SCHEMBL31184543 | 0.81 | POLB (0.50) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL28509012 | 0.81 | POLB (0.50) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL28509010 | 0.81 | POLB (0.50) | MALT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL28502106 | 0.80 | POLB (0.45) | MAPTHTTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |