Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905772 | 1.00 | MCHR1 (0.42) | MCHR1MALT1WDR5HTR1AHTR1D | |
| SCHEMBL30870559 | 0.89 | MAPT (0.49) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL28512461 | 0.89 | MAPT (0.49) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL29198240 | 0.85 | MALT1 (0.41) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL29198309 | 0.84 | MALT1 (0.42) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL28499919 | 0.83 | BRAF (0.37) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL30870584 | 0.83 | BRAF (0.37) | MALT1HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL30870626 | 0.81 | POLB (0.45) | MAPTLMNAALDH1A1HTTKDM4E | |
| SCHEMBL28502106 | 0.81 | POLB (0.45) | MAPTLMNAALDH1A1HTTKDM4E | |
| SCHEMBL30870533 | 0.80 | POLB (0.44) | MAPTLMNAALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |