Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055858 | 0.93 | TSHR (0.56) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL27745868 | 0.87 | L3MBTL1 (0.51) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL26189830 | 0.84 | TSHR (0.67) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL8621469 | 0.82 | TSHR (0.70) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL9011595 | 0.80 | TSHR (0.67) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL25311055 | 0.79 | TSHR (0.54) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL26813225 | 0.79 | TSHR (0.54) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL30186165 | 0.79 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL11895703 | 0.79 | TSHR (0.48) | TSHRTDP1L3MBTL1NAAAHRH4 | |
| SCHEMBL11895704 | 0.79 | TSHR (0.48) | TSHRTDP1L3MBTL1NAAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425661-A | Macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2024-01-19 | — | — | CN | disclosed |