SCHEMBL4055858

SCHEMBL4055858

C[CH]CCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NAAA Q02083 2/20 0.43
TAAR1 Q96RJ0 1/20 0.42
ALDH1A1 P00352 2/20 0.41
IDO1 P14902 1/20 0.41
LTA4H P09960 1/20 0.41
AGXT P21549 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DAO P14920 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
LMNA P02545 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29198543 0.93 TSHR (0.48) TSHRTDP1L3MBTL1NAAATAAR1
SCHEMBL27745868 0.86 L3MBTL1 (0.51) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL265425 0.84 TSHR (0.52) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL3438765 0.84 TSHR (0.52) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL5779691 0.80 TSHR (0.52) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL4079459 0.80 TSHR (0.52) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL1991359 0.79 TSHR (0.78) TSHRTDP1L3MBTL1NAAAIDO1
SCHEMBL1428305 0.79 TSHR (0.56) TSHRNAAAALDH1A1IDO1LTA4H
SCHEMBL6159679 0.79 TSHR (0.56) TSHRTDP1L3MBTL1NAAAALDH1A1
SCHEMBL1867995 0.79 TSHR (0.56) TSHRTDP1L3MBTL1NAAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113501774-B Method for synthesizing bromodifluoromethyl selenide compounds under metal-free condition 江苏省原子医学研究所 2023-02-28 CN claimed
CN-113501774-A Method for synthesizing bromodifluoromethyl selenide compounds under metal-free condition 江苏省原子医学研究所 2021-10-15 CN claimed
CN-106336384-A Synthetic method for forming oxazolidine-4-ketone 杭州师范大学 2017-01-18 CN claimed
CN-113501774-B Method for synthesizing bromodifluoromethyl selenide compounds under metal-free condition 江苏省原子医学研究所 2023-02-28 CN disclosed
CN-113501774-A Method for synthesizing bromodifluoromethyl selenide compounds under metal-free condition 江苏省原子医学研究所 2021-10-15 CN disclosed
CN-106336384-B A kind of synthetic method forming oxazolidine -4- ketone 杭州师范大学 2019-05-14 CN disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
WO-2009010871-A2 PYRAZOLE DERIVATIVES AS ANTAGONISTS OF ADENOSINE A3 RECEPTOR ADDEX PHARMA S.A. (CH) 2009-01-22 WO disclosed
US-6528455-B1 Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione BASF AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
EP-1237879-A1 PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-09-11 EP disclosed
WO-2001044204-A1 PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-06-21 WO disclosed