SCHEMBL29198567

SCHEMBL29198567

Cn1nc(C(F)F)c(C(N)=O)c1-c1cc(F)ccc1-c1cccc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.39
GRM5 P41594 1/20 0.37
CSNK1E P49674 9/20 0.35
CSNK1D P48730 7/20 0.35
MAPK14 Q16539 3/20 0.35
PRKD3 O94806 1/20 0.35
MAPK9 P45984 1/20 0.35
MAPKAPK2 P49137 1/20 0.35
MAPK10 P53779 1/20 0.35
ROCK1 Q13464 1/20 0.35
ACVR2B Q13705 1/20 0.35
MYLK Q15746 1/20 0.35
MAPK11 Q15759 1/20 0.35
PRKD2 Q9BZL6 1/20 0.35
NLK Q9UBE8 1/20 0.35
PI4KB Q9UBF8 1/20 0.35
ALK Q9UM73 1/20 0.35
TGFBR1 P36897 2/20 0.34
JAK2 O60674 1/20 0.34
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1763226 0.86 CSNK1E (0.41) DHODHCSNK1ECSNK1D
SCHEMBL3329484 0.86 CSNK1D (0.41) DHODHGRM5CSNK1ECSNK1DMAPK14
SCHEMBL28483197 0.86 DHODH (0.36) DHODHGRM5CSNK1ECSNK1DMAPK14
SCHEMBL18691186 0.85 POLB (0.35) DHODHCSNK1ECSNK1DPRKD3PRKD2
SCHEMBL18691184 0.85 CSNK1D (0.34) DHODHCSNK1ECSNK1DPRKD3PRKD2
SCHEMBL1762881 0.82 CSNK1D (0.41) DHODHCSNK1ECSNK1DPRKD3PRKD2
SCHEMBL30132981 0.82 CSNK1E (0.38) DHODHGRM5CSNK1ECSNK1DTGFBR1
SCHEMBL3865441 0.82 CSNK1D (0.38) CSNK1ECSNK1DGRM2
SCHEMBL27795834 0.81 MGLL (0.35) CSNK1ECSNK1D
SCHEMBL25437339 0.81 GRM2 (0.41) DHODHGRM5CSNK1ECSNK1DGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114617136-B Microbial compositions for promoting plant growth and treating plant diseases and methods of use FMC有限公司 2024-03-22 CN disclosed