Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL29199663

N.NC(=O)c1cccc(I)c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 10/20 0.57
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PARP15 Q460N3 2/20 0.47
PARP10 Q53GL7 2/20 0.47
TNKS O95271 1/20 0.47
PARP14 Q460N5 1/20 0.47
TNKS2 Q9H2K2 1/20 0.47
PARP2 Q9UGN5 1/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1259478 0.98 PARP1 (0.59) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL29532463 0.98 PARP1 (0.59) PARP1TSHRPOLBCYP3A4MAPT
Hydrochloric Acid SCHEMBL26628569 0.96 PARP1 (0.57) PARP1TSHRPOLBCYP3A4MAPT
Ammonia Solution, Strong SCHEMBL9121446 0.84 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL36694 0.81 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL31021028 0.81 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL1926964 0.80 MTOR (0.52) L3MBTL1MEN1KMT2AMTORHDAC1
SCHEMBL2093436 0.80 HDAC1 (0.44) PARP1TDP1L3MBTL1MTORHDAC1
SCHEMBL3673834 0.79 ATM (0.58) TDP1L3MBTL1MTORHDAC1HDAC2
SCHEMBL18079795 0.79 CES2 (0.54) MTORHDAC1HDAC2GRM5F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940504-A Triazole containing polymers and methods of use thereof 威廉马什莱斯大学 2024-04-26 CN disclosed