Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843601 | 0.95 | ATM (0.60) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL3839245 | 0.93 | ATM (0.71) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL3845298 | 0.91 | ATM (0.56) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL3838631 | 0.86 | AKR1C3 (0.55) | ATMTDP1L3MBTL1 | |
| SCHEMBL3841059 | 0.86 | ATM (0.55) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL18079795 | 0.85 | CES2 (0.54) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL3840674 | 0.85 | POLB (0.51) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL3670492 | 0.84 | SRD5A2 (0.53) | ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7455315 | 0.83 | AKR1C3 (0.59) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL40282 | 0.83 | CA12 (0.58) | TDP1L3MBTL1ALDH1A1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100343256-C | Biaryl substituted diazabicycloalkane amides as nicotinic acetylcholine agonists | ASTRAZENECA AB (SE) | 2007-10-17 | — | — | CN | claimed |
| CN-1678615-A | Biaryl substituted diazabicycloalkanes as nicotinic acetylcholine antagonists | ASTRAZENECA AB (SE) | 2005-10-05 | — | — | CN | claimed |
| CN-1675215-A | Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists | ASTRAZENECA AB (SE) | 2005-09-28 | — | — | CN | claimed |
| WO-2024117245-A1 | POLYARYL ETHER KETONE RESIN COMPOSITION, MOLDED ARTICLE OF SAME AND METHOD FOR PRODUCING POLYARYL ETHER KETONE RESIN COMPOSITION | 本州化学工業株式会社 | 2024-06-06 | — | — | WO | disclosed |
| WO-2020045316-A1 | MODIFIER FOR POLYMER, PRODUCTION METHOD FOR MODIFIED CONJUGATED-DIENE POLYMER, MODIFIED CONJUGATED-DIENE POLYMER, RUBBER COMPOSITION, TIRE, AND RUBBER BELT | 宇部興産株式会社 | 2020-03-05 | — | — | WO | disclosed |
| US-10461266-B2 | Luminescent compounds and methods of using same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-10-29 | — | — | US | disclosed |
| WO-2019198607-A1 | ALKENYL-GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, AND CURED OBJECT OBTAINED THEREFROM | 日本化薬株式会社 | 2019-10-17 | — | — | WO | disclosed |
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-12-14 | — | — | US | disclosed |
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-12-14 | — | — | US | disclosed |
| US-20160264581-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | Janssen Pharmaceuticals, Inc. | 2016-09-15 | — | — | US | disclosed |
| US-20030195301-A1 | Polyarylene copolymers and proton-conductive membrane | JSR CORPORATION (JP) | 2003-10-16 | — | — | US | disclosed |
| US-20030173547-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1329444-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR Corporation (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6555626-B2 | Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity | JSR CORPORATION (JP) | 2003-04-29 | — | — | US | disclosed |
| US-20020172652-A1 | Composition for film formation and material for insulating film formation | JSR CORPORATION (JP) | 2002-11-21 | — | — | US | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-1245638-A1 | Composition for insulating film formation | JSR Corporation (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-20010037000-A1 | Polyarylene copolymers and proton-conductive membrane | JSR CORPORATION (JP) | 2001-11-01 | — | — | US | disclosed |
| EP-1138712-A2 | Polyarylene copolymers and proton-conductive membrane | JSR Corporation (JP) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170358761-A1 | Luminescent Compounds and Methods of Using Same | CRY2, CYBA, TYR | ATM 1242/4885TDP1 1175/4885L3MBTL1 506/4885 |
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | ATM 2662/4885TDP1 1026/4885L3MBTL1 4081/4885 |
| US-20160264581-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | PNPO, ITPA, PDXK | ATM 2662/4885TDP1 1026/4885L3MBTL1 4081/4885 |
| US-20020172652-A1 | Composition for film formation and material for insulating film formation | VCL, BMI1, PUF60 | ATM 1417/4885TDP1 1971/4885L3MBTL1 2698/4885 |
| US-10461266-B2 | Luminescent compounds and methods of using same | CRY2, CYBA, TYR | ATM 1242/4885TDP1 1175/4885L3MBTL1 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.