Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24965166 | 0.79 | SMN1; SMN2 (0.40) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 | |
| SCHEMBL24965167 | 0.79 | SMN1; SMN2 (0.40) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 | |
| Hydrochloric Acid SCHEMBL11683741 | 0.77 | RIPK1 (0.32) | — | |
| SCHEMBL13104142 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27028681 | 0.68 | NAALAD2 (0.44) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 | |
| SCHEMBL24633751 | 0.68 | NAALAD2 (0.44) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 | |
| SCHEMBL202719 | 0.67 | NAALAD2 (0.38) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 | |
| SCHEMBL24633935 | 0.67 | TSHR (0.40) | SMN1; SMN2 | |
| SCHEMBL6118149 | 0.66 | NR1H2 (0.34) | — | |
| SCHEMBL8231008 | 0.65 | NAALAD2 (0.37) | EPHX1ALDH1A1POLBSMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751124-A | Spiro oxindole compounds and application thereof in preparing antiviral protease inhibitor medicines | 南京药石科技股份有限公司 | 2024-03-22 | — | — | CN | disclosed |