Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125170 | 0.85 | ABCG2 (0.65) | ABCG2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL1921849 | 0.80 | ABCG2 (0.53) | ABCG2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL3759489 | 0.79 | F12 (0.52) | MAPTKDM4EHTTALOX12L3MBTL1 | |
| SCHEMBL23202903 | 0.78 | RAB9A (0.53) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL30827864 | 0.78 | RAB9A (0.53) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL28500108 | 0.78 | ALDH1A1 (0.50) | KMT2AMEN1MAPTMAPK1HTT | |
| SCHEMBL4497329 | 0.77 | ABCG2 (0.58) | ABCG2KMT2AMEN1MAPTHTT | |
| SCHEMBL31098979 | 0.77 | TNF (0.57) | ABCG2MAPK1NPSR1HPGDEGFR | |
| SCHEMBL20356687 | 0.77 | NPC1 (0.56) | ABCG2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL20852287 | 0.77 | EGFR (0.60) | ABCG2KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | disclosed |