SCHEMBL2920007

SCHEMBL2920007

C/C(=C\c1cccc([N+](=O)[O-])c1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 2/20 0.70
FBP1 P09467 2/20 0.59
NFE2L2 Q16236 2/20 0.57
AKR1C3 P42330 1/20 0.56
MAPT P10636 1/20 0.54
MAOB P27338 1/20 0.54
ALDH1A1 P00352 2/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
VCP P55072 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 1/20 0.51
HIF1A Q16665 1/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
ITGB2 P05107 1/20 0.50
ICAM1 P05362 1/20 0.50
ITGAL P20701 1/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444743 1.00 GLO1 (0.70) GLO1FBP1NFE2L2AKR1C3MAPT
SCHEMBL2920009 1.00 GLO1 (0.70) GLO1FBP1NFE2L2AKR1C3MAPT
SCHEMBL11100277 0.86 GLO1 (0.68) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL11100274 0.86 GLO1 (0.68) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL9401844 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7271725 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7271722 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7277503 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL1095056 0.84 GLO1 (0.65) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL1095055 0.84 GLO1 (0.65) GLO1FBP1NFE2L2MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
CN-110590529-A Preparation method of 1-aryl-2-acetone compound 浙江医药高等专科学校 2019-12-20 CN disclosed
EP-2226192-B1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD (IL) 2016-08-31 EP disclosed
EP-2226116-B1 Drying tube, preparation and use thereof ORIDION MEDICAL 1987 LTD (IL) 2016-04-20 EP disclosed
CN-105056916-A Restricted access type chiral chromatography MC (monolithic column) as well as preparation method and application thereof UNIV CHINA PHARMA 2015-11-18 CN disclosed
US-20150283519-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD. (IL) 2015-10-08 US disclosed
US-9090766-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2015-07-28 US disclosed
US-9067035-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2015-06-30 US disclosed
US-20140230652-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL (1987) LTD. (IL) 2014-08-21 US disclosed
EP-0047119-B1 CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION, AND INTERMEDIATES USEFUL THEREIN PFIZER INC. (US) 1984-05-09 EP disclosed
EP-0050977-B1 CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS AND A PROCESS FOR PRODUCING SAME PFIZER INC. (US) 1983-09-14 EP disclosed
US-4343813-A ANTIANAPHYLACTIC AGENTS PFIZER INC. (US) 1982-08-10 US disclosed
US-4331683-A SENSITIZATION, ANTIALLERGENS PFIZER INC. (US) 1982-05-25 US disclosed
EP-0050977-A1 Carboxamide compounds as SRS-A antagonists and a process for producing same PFIZER INC. (US) 1982-05-05 EP disclosed
EP-0047119-A1 Carboxamide compounds as SRS-A antagonists, pharmaceutical compositions containing them, processes for the preparation, and intermediates useful therein PFIZER INC. (US) 1982-03-10 EP disclosed
US-4296129-A ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS PFIZER, INC. (US) 1981-10-20 US disclosed
US-4296120-A ANTIANAPHYLACTIC PFIZER INC. (US) 1981-10-20 US disclosed
US-4182897-A ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES TORII & CO., LTD. (JP) 1980-01-08 US disclosed