SCHEMBL6444743

SCHEMBL6444743

CC(=Cc1cccc([N+](=O)[O-])c1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 2/20 0.70
FBP1 P09467 2/20 0.59
NFE2L2 Q16236 2/20 0.57
AKR1C3 P42330 1/20 0.56
MAPT P10636 1/20 0.54
MAOB P27338 1/20 0.54
ALDH1A1 P00352 2/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
VCP P55072 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 1/20 0.51
HIF1A Q16665 1/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
ITGB2 P05107 1/20 0.50
ICAM1 P05362 1/20 0.50
ITGAL P20701 1/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2920007 1.00 GLO1 (0.70) GLO1FBP1NFE2L2AKR1C3MAPT
SCHEMBL2920009 1.00 GLO1 (0.70) GLO1FBP1NFE2L2AKR1C3MAPT
SCHEMBL11100277 0.86 GLO1 (0.68) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL11100274 0.86 GLO1 (0.68) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL9401844 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7271725 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7271722 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL7277503 0.85 GLO1 (0.86) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL1095056 0.84 GLO1 (0.65) GLO1FBP1NFE2L2MAPTMAOB
SCHEMBL1095055 0.84 GLO1 (0.65) GLO1FBP1NFE2L2MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105056916-A Restricted access type chiral chromatography MC (monolithic column) as well as preparation method and application thereof UNIV CHINA PHARMA 2015-11-18 CN disclosed
EP-1146083-B1 USE OF A RESIN MATERIAL FOR ELECTRICAL INSULATING AND ELECTRIC WIRE AND CABLE USING THE SAME JAPAN POLYOLEFINS CO LTD (JP) 2005-01-05 EP disclosed
EP-1314721-A1 NOVEL PROPENOHYDROXAMIC ACID DERIVATIVES WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2003-05-28 EP disclosed
US-6479590-B1 Electrical insulating resin material, electrical insulating material, and electric wire and cable using the same JAPAN POLYOLEFINS CO., LTD. (JP) 2002-11-12 US disclosed
EP-1146083-A1 ELECTRICAL INSULATING RESIN MATERIAL, ELECTRICAL INSULATING MATERIAL, AND ELECTRIC WIRE AND CABLE USING THE SAME Japan Polyolefins Co., Ltd. (JP) 2001-10-17 EP disclosed