Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 8/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184744 | 0.88 | HTRA1 (0.46) | HTRA1POLBKDM4EALDH1A1GAA | |
| SCHEMBL28529255 | 0.85 | HTRA1 (0.48) | HTRA1F2RMAPTTACR1RORC | |
| SCHEMBL24645690 | 0.85 | HTRA1 (0.48) | HTRA1F2RMAPTTACR1RORC | |
| SCHEMBL6183705 | 0.85 | HTRA1 (0.48) | HTRA1F2RMAPTTACR1RORC | |
| SCHEMBL28531769 | 0.82 | TACR1 (0.42) | HTRA1POLBF2RMAPTTACR1 | |
| SCHEMBL28537494 | 0.81 | TACR1 (0.46) | HTRA1F2RMAPTTACR1RORC | |
| SCHEMBL28531832 | 0.80 | CYP3A4 (0.42) | POLBKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL28536977 | 0.78 | TACR1 (0.43) | HTRA1POLBKDM4EALDH1A1GAA | |
| SCHEMBL28539977 | 0.78 | TACR1 (0.43) | HTRA1POLBKDM4EALDH1A1GAA | |
| SCHEMBL21619693 | 0.77 | TACR1 (0.48) | MAPTTACR1RORCCETPP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |