Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.60 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.60 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802669 | 1.00 | NLRP3 (0.72) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL29200388 | 0.88 | NLRP3 (0.72) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL29200413 | 0.88 | MEN1 (0.66) | NLRP3KMT2AMEN1MAPTKCNJ5 | |
| SCHEMBL30802671 | 0.88 | NLRP3 (0.72) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL30802681 | 0.88 | MEN1 (0.66) | NLRP3KMT2AMEN1MAPTKCNJ5 | |
| SCHEMBL30802660 | 0.87 | KMT2A (0.72) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL29200430 | 0.87 | KMT2A (0.72) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL21620304 | 0.82 | ALDH1A1 (0.74) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL29200447 | 0.81 | KMT2A (0.57) | NLRP3KMT2AMEN1MAPTLMNA | |
| SCHEMBL30802694 | 0.81 | KMT2A (0.57) | NLRP3KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |