Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483338 | 0.82 | MEN1 (0.70) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL4304223 | 0.82 | MEN1 (1.00) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL10841580 | 0.81 | MEN1 (0.68) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL4554499 | 0.78 | HSD17B10 (0.60) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL11429178 | 0.78 | MEN1 (0.64) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL17932837 | 0.77 | USP2 (0.63) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL5819195 | 0.77 | KMT2A (0.57) | KMT2AMEN1HSD17B10USP2THRB | |
| SCHEMBL11287043 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9749098 | 0.76 | MEN1 (0.69) | KMT2AMEN1HSD17B10USP2ALDH1A1 | |
| SCHEMBL20016685 | 0.76 | MEN1 (0.79) | KMT2AMEN1HSD17B10USP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |