Urea

Urea

SCHEMBL29200424

NC(N)=O.O=C(Nc1cccc(F)c1)Nc1cccc(CCl)c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.60
RAB9A P51151 7/20 0.60
MEN1 O00255 5/20 0.60
MTOR P42345 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 2/20 0.51
MARS1 P56192 1/20 0.51
NPC1 O15118 6/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TSHR P16473 1/20 0.50
AURKA O14965 1/20 0.50
RPS6KB1 P23443 1/20 0.50
AURKB Q96GD4 1/20 0.50
CASP3 P42574 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
POLB P06746 2/20 0.49
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30802661 0.96 RAB9A (0.65) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL29200400 0.96 RAB9A (0.65) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL29200375 0.85 RAB9A (0.63) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL30802672 0.82 RAB9A (0.62) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL29200418 0.82 RAB9A (0.62) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL29200398 0.82 MEN1 (0.62) KMT2ARAB9AMEN1MAPTLMNA
SCHEMBL30802678 0.82 MEN1 (0.62) KMT2ARAB9AMEN1MAPTLMNA
SCHEMBL30851500 0.81 RAB9A (0.79) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL27193042 0.81 RAB9A (0.79) KMT2ARAB9AMEN1MTORTAAR1
SCHEMBL29200402 0.79 MEN1 (0.74) KMT2ARAB9AMEN1MTORMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658868-A Benzamide derivative and preparation method and application thereof 中山大学 2024-03-08 CN disclosed