Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 9/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095806 | 0.78 | MAPT (0.49) | FFAR4MRGPRX4MAOBRXRARXRB | |
| SCHEMBL31285263 | 0.78 | KEAP1 (0.39) | FFAR4KEAP1NFE2L2MRGPRX4 | |
| SCHEMBL8761479 | 0.74 | MAPT (0.51) | FFAR4MRGPRX4MAOBRXRARXRB | |
| SCHEMBL31285324 | 0.71 | BRD4 (0.41) | FFAR4MRGPRX4MCL1 | |
| SCHEMBL29621948 | 0.70 | MAPT (0.56) | FFAR4MAOBRXRARXRBRXRG | |
| SCHEMBL10252960 | 0.70 | RXRA (0.57) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL19667514 | 0.70 | MCL1 (0.56) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL29200479 | 0.69 | FFAR4 (0.44) | FFAR4KEAP1NFE2L2MRGPRX4RXRA | |
| SCHEMBL31643595 | 0.69 | RXRA (0.49) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL31405064 | 0.69 | MAPT (0.50) | FFAR4MRGPRX4MAOBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658947-A | 5- (substituted aryl) -1,2, 5-thiadiazolin-3-one compounds with protein tyrosine phosphatase inhibiting effect | 杭州中美华东制药有限公司 | 2024-03-08 | — | — | CN | disclosed |