Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517510 | 0.89 | KDM4E (0.43) | EPHX2KDM4ESTING1CYP2D6CYP2C9 | |
| SCHEMBL29200547 | 0.89 | KDM4E (0.54) | EPHX2KDM4ESTING1CYP2D6CYP2C9 | |
| SCHEMBL24467571 | 0.88 | KDM4E (0.47) | EPHX2KDM4ESTING1CYP2D6CYP2C9 | |
| SCHEMBL29200533 | 0.84 | PTGER4 (0.41) | KDM4ESTING1ALDH1A1NPC1RAB9A | |
| SCHEMBL29200485 | 0.82 | IRAK4 (0.33) | STING1 | |
| SCHEMBL29200502 | 0.81 | PDE4A (0.38) | — | |
| SCHEMBL19451648 | 0.81 | STING1 (0.47) | EPHX2KDM4ESTING1CYP2D6CYP2C9 | |
| SCHEMBL19437488 | 0.80 | CYP2C9 (0.58) | KDM4ESTING1CYP2D6CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23227989 | 0.80 | STING1 (0.47) | EPHX2KDM4ESTING1CYP2D6CYP2C9 | |
| SCHEMBL22121239 | 0.79 | STING1 (0.43) | EPHX2KDM4ESTING1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |