Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906815 | 0.87 | PTGER4 (0.45) | PTGER4KMT2AMEN1STING1SMN1; SMN2 | |
| SCHEMBL29200576 | 0.87 | ALDH1A1 (0.40) | PTGER4RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL29200502 | 0.85 | PDE4A (0.38) | PTGER4 | |
| SCHEMBL29200592 | 0.84 | EPHX2 (0.43) | KMT2AMEN1STING1SMN1; SMN2NPC1 | |
| SCHEMBL29200485 | 0.83 | IRAK4 (0.33) | STING1 | |
| SCHEMBL21789934 | 0.79 | TSHR (0.41) | PTGER4KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22121045 | 0.77 | TSHR (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23637198 | 0.77 | TSHR (0.40) | PTGER4KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28508495 | 0.76 | PTGER4 (0.40) | PTGER4KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28509702 | 0.75 | ALDH1A1 (0.43) | PTGER4RAB9AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |