Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905708 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29200592 | 0.89 | EPHX2 (0.43) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29200576 | 0.85 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9AMAPTLMNA | |
| SCHEMBL29200545 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19437452 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29200495 | 0.83 | MAPT (0.38) | KDM4EALDH1A1MAPTLMNAGAA | |
| SCHEMBL19451647 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19436485 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22121243 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19436543 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |