Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.43 |
| ▸ | JAK1 | P23458 | 6/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377218 | 0.85 | RORC (0.43) | RORCGPR119NAMPTUSP30KDM4E | |
| SCHEMBL29200673 | 0.81 | NAMPT (0.41) | JAK2JAK1RORCGPR119NAMPT | |
| SCHEMBL19063842 | 0.81 | NR1H2 (0.41) | JAK2JAK1RORCGPR119NAMPT | |
| SCHEMBL19063844 | 0.81 | NR1H2 (0.41) | JAK2JAK1RORCGPR119NAMPT | |
| SCHEMBL10105773 | 0.81 | RORC (0.46) | RORCGPR119NAMPTUSP30KDM4E | |
| SCHEMBL30922985 | 0.81 | GPR119 (0.40) | JAK2JAK1RORCGPR119NAMPT | |
| SCHEMBL2930634 | 0.79 | USP2 (0.40) | JAK2JAK1GPR119 | |
| SCHEMBL2937600 | 0.79 | USP2 (0.40) | JAK2JAK1GPR119 | |
| SCHEMBL2930976 | 0.79 | USP2 (0.40) | JAK2JAK1GPR119 | |
| SCHEMBL2930633 | 0.79 | USP2 (0.40) | JAK2JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659022-A | Ureido substituted pyridine compound, pharmaceutical composition containing ureido substituted pyridine compound and medical application of ureido substituted pyridine compound | 苏州阿尔脉生物科技有限公司 | 2024-03-08 | — | — | CN | disclosed |