Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.42 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801949 | 0.86 | KDR (0.54) | FLT1KDRKDM5AKDM2BKDM4C | |
| SCHEMBL14710604 | 0.79 | KDM4C (0.43) | DHODHKDRKDM5AKDM2BKDM4C | |
| SCHEMBL12727152 | 0.75 | KDR (0.53) | FLT1KDRALDH1A1LMNAMAPT | |
| SCHEMBL4796730 | 0.74 | KDR (0.52) | FLT1KDRKDM4CLMNA | |
| SCHEMBL12457299 | 0.72 | NSD2 (0.40) | KDRKDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL10082090 | 0.71 | TAAR1 (0.48) | KDM4CALDH1A1LMNA | |
| SCHEMBL20028095 | 0.71 | SMN1; SMN2 (0.55) | KDRALDH1A1LMNAMAPT | |
| SCHEMBL15013223 | 0.70 | HRH3 (0.41) | KDRKDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL14788595 | 0.70 | KDM4C (0.40) | KDRKDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL8214146 | 0.68 | NUDT14 (0.50) | NUDT14NUDT5TNK2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761399-B | Imidazole carboxamide derivatives as bruton's tyrosine kinase inhibitors | 河南知微生物医药有限公司 | 2024-03-26 | — | — | CN | disclosed |