Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489832 | 0.74 | G6PC1 (0.52) | G6PC1NPC1 | |
| SCHEMBL3490011 | 0.73 | G6PC1 (0.46) | ROCK2G6PC1NPC1CYP1A2CYP2D6 | |
| SCHEMBL28885499 | 0.72 | CYP1A2 (0.61) | MKNK2MAP4K4ROCK2PRKACAROCK1 | |
| SCHEMBL21847184 | 0.72 | CYP1A2 (0.61) | MKNK2MAP4K4ROCK2PRKACAROCK1 | |
| SCHEMBL31015289 | 0.72 | MKNK2 (0.53) | MKNK2MAP4K4ROCK2PRKACAROCK1 | |
| SCHEMBL5313268 | 0.72 | MKNK2 (0.53) | MKNK2MAP4K4ROCK2PRKACAROCK1 | |
| SCHEMBL21914766 | 0.70 | RAB9A (0.62) | NPC1CYP1A2 | |
| SCHEMBL29201275 | 0.70 | RAB9A (0.62) | NPC1CYP1A2 | |
| SCHEMBL12966330 | 0.69 | MKNK2 (0.46) | MKNK2MAP4K4ROCK2PRKACAROCK1 | |
| SCHEMBL3488129 | 0.68 | ATM (0.44) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914280-B | 6H-thieno [2,3-e ] [1,2,4] triazolo [3,4-c ] [1,2,4] triazab derivatives | 阿尤米制药公司 | 2024-05-03 | — | — | CN | disclosed |