Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470700 | 0.89 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BBRD4 | |
| SCHEMBL22579112 | 0.78 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551920 | 0.76 | ADORA2A (0.67) | ADORA2AADORA1ADORA2B | |
| SCHEMBL28804334 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL4584433 | 0.74 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4583598 | 0.73 | ADORA2A (0.55) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4585332 | 0.72 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL29987316 | 0.70 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BBRD4 | |
| SCHEMBL4585883 | 0.70 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BBRD4 | |
| SCHEMBL4585557 | 0.70 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |