SCHEMBL29201304

SCHEMBL29201304

COc1ccc2[nH]c(C(=O)O)c(CCC3Oc4ccccc4O3)c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
KDM4E B2RXH2 4/20 0.65
HPGD P15428 4/20 0.65
HSD17B10 Q99714 3/20 0.65
POLB P06746 1/20 0.60
MDM2 Q00987 1/20 0.60
GPR17 Q13304 1/20 0.53
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MTNR1A P48039 4/20 0.49
MTNR1B P49286 4/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 2/20 0.48
APEX1 P27695 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
AKR1C2 P52895 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28697114 0.88 NQO2 (0.63) ALDH1A1KDM4EHPGDHSD17B10MEN1
SCHEMBL3953151 0.80 KDM4E (0.79) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL3036074 0.77 KDM4E (0.74) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL9127829 0.77 KDM4E (0.86) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL1345727 0.77 KDM4E (0.73) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL29628842 0.76 KDM4E (0.76) ALDH1A1KDM4EHPGDHSD17B10POLB
Hydrochloric Acid SCHEMBL1343869 0.76 ALDH1A1 (0.72) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL3103301 0.75 MEN1 (0.81) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL15428037 0.75 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL6703468 0.74 KDM4E (0.69) ALDH1A1KDM4EHPGDHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085179-B Preparation method of N-acetyl-5-methoxy tryptamine 福建科宏生物工程股份有限公司 2024-05-03 CN disclosed