Phosphine

Phosphine

SCHEMBL29201537

P.c1ccc(-c2ccc3cc2-3)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.48
MEN1 O00255 1/20 0.46
APAF1 O14727 1/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
XBP1 P17861 1/20 0.46
PTBP1 P26599 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
GALK1 P51570 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5108278 0.94 MEN1 (0.52) BACE1MEN1APAF1NPC1LMNA
SCHEMBL31402541 0.89 MEN1 (0.58) BACE1MEN1APAF1NPC1LMNA
SCHEMBL779467 0.89 MEN1 (0.58) BACE1MEN1APAF1NPC1LMNA
SCHEMBL28623610 0.85 BACE1 (0.46) BACE1MEN1APAF1NPC1LMNA
SCHEMBL29610886 0.84 MEN1 (0.65) BACE1MEN1APAF1NPC1LMNA
SCHEMBL29026493 0.84 KIF11 (0.41) BACE1MEN1APAF1NPC1LMNA
SCHEMBL15657040 0.84 MEN1 (0.39) BACE1MEN1APAF1NPC1LMNA
SCHEMBL6754212 0.82 ALDH1A1 (0.55) BACE1MEN1APAF1NPC1LMNA
SCHEMBL21481286 0.82 MEN1 (0.50) MEN1APAF1NPC1LMNAMAPT
SCHEMBL26820200 0.82 ESR2 (0.52) BACE1MEN1APAF1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924317-A N-containing organic compounds and their use in organic light emitting devices and panels 武汉天马微电子有限公司上海分公司 2024-04-26 CN disclosed