Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216783 | 0.85 | GAA (0.53) | BRD4ALDH1A1KDM4EPKMTHRB | |
| SCHEMBL1576006 | 0.84 | HPGD (0.50) | EPHX1FAAHKDM4EPKM | |
| SCHEMBL13451670 | 0.81 | BRD4 (0.50) | BRD4EPHX1KDM4EPKMTHRB | |
| SCHEMBL13451380 | 0.81 | BRD4 (0.47) | BRD4ALDH1A1EPHX1FAAHKDM4E | |
| SCHEMBL13498638 | 0.81 | BRD4 (0.47) | BRD4ALDH1A1EPHX1FAAHKDM4E | |
| SCHEMBL3950205 | 0.81 | EPHX2 (0.39) | EPHX1KDM4E | |
| SCHEMBL5250700 | 0.81 | BRD4 (0.42) | BRD4ALDH1A1EPHX1FAAHKDM4E | |
| SCHEMBL4472595 | 0.79 | ITGB3 (0.36) | GAA | |
| SCHEMBL13597243 | 0.78 | POLB (0.48) | BRD4ALDH1A1PKMTHRBATM | |
| SCHEMBL3310103 | 0.78 | BRD4 (0.48) | BRD4ALDH1A1EPHX1FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |