Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949719 | 0.89 | EPHX2 (0.38) | EPHX2EPHX1CYP1A2TDP1GNAI3 | |
| SCHEMBL4472595 | 0.83 | ITGB3 (0.36) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11832401 | 0.81 | EPHX2 (0.41) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL3951389 | 0.81 | EPHX2 (0.40) | EPHX2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL29201749 | 0.81 | BRD4 (0.44) | EPHX1KDM4E | |
| SCHEMBL9216783 | 0.80 | GAA (0.53) | TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL19851879 | 0.80 | EPHX2 (0.36) | EPHX2EPHX1CYP1A2TDP1GNAI3 | |
| SCHEMBL2422675 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL12641 | 0.79 | GNAI3 (0.45) | EPHX2EPHX1CYP1A2TDP1GNAI3 | |
| SCHEMBL1501881 | 0.79 | AKR1C3 (0.43) | EPHX2EPHX1CYP1A2TDP1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| CN-1040322-C | Pyrimidines compounds | UBE INDUSTRIES (JP) | 1998-10-21 | — | — | CN | disclosed |