SCHEMBL29201750

SCHEMBL29201750

CC(C(=O)O)N(C(=O)OCC1c2ccccc2-c2ccccc21)c1ccc2ccccc2c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.39
FABP7 O15540 2/20 0.39
EPHX2 P34913 1/20 0.38
KMT2A Q03164 2/20 0.37
CASP3 P42574 2/20 0.37
MDM4 O15151 1/20 0.35
TP53 P04637 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763559 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL29474439 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL599683 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL1905118 0.87 FABP5 (0.44) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL5233109 0.86 FABP5 (0.43) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL18301546 0.86 GLI1 (0.41) FABP5FABP7EPHX2
SCHEMBL5494109 0.84 FABP5 (0.43) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL31054358 0.84 PPARG (0.40) FABP5FABP7EPHX2KMT2AMDM4
SCHEMBL28916981 0.83 CHRNB2 (0.40) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL29713658 0.83 CHRNB2 (0.40) FABP5FABP7EPHX2KMT2ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924414-A Compound for promoting Abeta clearance and preparation method and application thereof 中山大学 2024-04-26 CN disclosed
CN-117924414-A Compound for promoting Abeta clearance and preparation method and application thereof 中山大学 2024-04-26 CN disclosed