SCHEMBL599683

SCHEMBL599683

C[C@@H](C(=O)O)N(C(=O)OCC1c2ccccc2-c2ccccc21)c1ccc2ccccc2c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.39
FABP7 O15540 2/20 0.39
EPHX2 P34913 1/20 0.38
KMT2A Q03164 2/20 0.37
CASP3 P42574 2/20 0.37
MDM4 O15151 1/20 0.35
TP53 P04637 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763559 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL29474439 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL29201750 1.00 FABP5 (0.39) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL1905118 0.87 FABP5 (0.44) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL5233109 0.86 FABP5 (0.43) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL18301546 0.86 GLI1 (0.41) FABP5FABP7EPHX2
SCHEMBL5494109 0.84 FABP5 (0.43) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL31054358 0.84 PPARG (0.40) FABP5FABP7EPHX2KMT2AMDM4
SCHEMBL28916981 0.83 CHRNB2 (0.40) FABP5FABP7EPHX2KMT2ACASP3
SCHEMBL29713658 0.83 CHRNB2 (0.40) FABP5FABP7EPHX2KMT2ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP Bicyclerd Limited (GB) 2025-08-14 US disclosed
US-20250230191-A1 PEPTIDE LIGANDS FOR BINDING TO MT1-MMP BICYCLETX LIMITED (GB) 2025-07-17 US disclosed
US-12318454-B2 Bicyclic peptide ligands specific for MT1-MMP Bicyclerd Limited (GB) 2025-06-03 US disclosed
US-20250057993-A1 LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PSMA-EXPRESSING CANCERS Universität Heidelberg (DE) 2025-02-20 US disclosed
CN-119431260-A Targeting prostate specific membranes radiolabeled compounds for antigens 省卫生服务机构 2025-02-14 CN disclosed
EP-3452096-B1 BICYCLIC PEPTIDE-TOXIN CONJUGATES SPECIFIC FOR MT1-MMP BICYCLERD LTD (GB) 2025-01-29 EP disclosed
EP-4473980-A2 LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PSMA-EXPRESSING CANCERS Universität Heidelberg (DE) 2024-12-11 EP disclosed
CN-114401947-B Targeting prostate specific membranes radiolabeled compounds for antigens 省卫生服务机构 2024-11-29 CN disclosed
CN-116217505-B Novel marker targeting agents for diagnosis or treatment of cancers expressing prostate specific membrane antigen 南京医科大学 2024-10-01 CN disclosed
WO-2024193724-A1 NEW LABELING TARGETING AGENT FOR DIAGNOSING OR TREATING PROSTATE-SPECIFIC MEMBRANE ANTIGEN EXPRESSING CANCER 南京医科大学 2024-09-26 WO disclosed
EP-0999220-A2 Low molecular weight peptidomimetic growth hormone secretagogues Genentech, Inc. (US) 2000-05-10 EP disclosed
US-6034216-A Low molecular weight peptidomimetic growth hormone secretagogues GENENTECH INC. (US) 2000-03-07 US disclosed
WO-1999065932-A1 TETRAPEPTIDES, ANALOGS AND PEPTIDOMIMETICS WHICH BIND SELECTIVELY MAMMALIAN OPIOID RECEPTORS SEPRACOR, INC. (US) 1999-12-23 WO disclosed
WO-1999011657-A1 1-AMINO-7-ISOQUINOLINE DERIVATIVES AS SERINE PROTEASE INHIBITORS PROTEUS MOLECULAR DESIGN LTD. (GB) 1999-03-11 WO disclosed
WO-1999011658-A1 META-BENZAMIDINE DERIVATIVES AS SERIN PROTEASE INHIBITORS PROTEUS MOLECULAR DESIGN LTD. (GB) 1999-03-11 WO disclosed
US-5798337-A USED TO PROMOTE GROWTH IN MAMMALS EITHER ALONE OR IN COMBINATION WITH OTHER GROWTH PROMOTING COMPOUNDS GENENTECH, INC. (US) 1998-08-25 US disclosed
US-5710129-A Inhibitors of SH2-mediated processes ARIAD PHARMACEUTICALS, INC. (US) 1998-01-20 US disclosed
EP-0792289-A1 LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES GENENTECH, INC. (US) 1997-09-03 EP disclosed
WO-1997031016-A2 NEW INHIBITORS OF SH2-MEDIATED PROCESSES ARIAD PHARMACEUTICALS, INC. (US) 1997-08-28 WO disclosed
WO-1996015148-A2 LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES GENENTECH, INC. (US) 1996-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230191-A1 PEPTIDE LIGANDS FOR BINDING TO MT1-MMP MMP11, MMP3, ANPEP FABP5 1749/4885FABP7 747/4885EPHX2 2634/4885
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP MMEL1, MMP3, TIMP3 FABP5 1547/4885FABP7 1488/4885EPHX2 3396/4885
US-12318454-B2 Bicyclic peptide ligands specific for MT1-MMP MMEL1, MMP3, TIMP3 FABP5 1547/4885FABP7 1488/4885EPHX2 3396/4885
US-20250057993-A1 LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PSMA-EXPRESSING CANCERS KLK3, FOLH1, PSMA3 FABP5 2421/4885FABP7 2262/4885EPHX2 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.