Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27151420 | 0.87 | SMN1; SMN2 (0.54) | CHRM4KDM4EPKM | |
| SCHEMBL27140967 | 0.87 | SMN1; SMN2 (0.54) | CHRM4KDM4EPKM | |
| SCHEMBL8478310 | 0.86 | GPR119 (0.57) | CHRM4KDM4EPKMCHRM3 | |
| SCHEMBL8474293 | 0.84 | KDM4E (0.56) | CHRM4KDM4EPKM | |
| SCHEMBL27271703 | 0.84 | KDM4E (0.56) | KDM4EPKM | |
| SCHEMBL3251863 | 0.84 | KDM4E (0.58) | CHRM4KDM4EPKM | |
| SCHEMBL35211912 | 0.84 | KDM4E (0.55) | KDM4EPKM | |
| SCHEMBL18497603 | 0.83 | KDM4E (0.57) | CHRM4KDM4EPKM | |
| SCHEMBL5717213 | 0.83 | KDM4E (0.59) | KDM4EPKM | |
| SCHEMBL3406000 | 0.83 | CHRM4 (0.54) | CHRM4KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |