Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23250043 | 0.85 | SMN1; SMN2 (0.52) | CHRM4KDM4EPKM | |
| SCHEMBL8060432 | 0.83 | JAK2 (0.58) | CHRM4ACHEBCHEKDM4EPKM | |
| SCHEMBL8056077 | 0.83 | JAK2 (0.58) | CHRM4ACHEBCHEKDM4EPKM | |
| SCHEMBL8056082 | 0.83 | JAK2 (0.58) | CHRM4ACHEBCHEKDM4EPKM | |
| SCHEMBL4470679 | 0.83 | JAK2 (0.58) | CHRM4ACHEBCHEKDM4EPKM | |
| SCHEMBL29201760 | 0.83 | CHRM4 (0.60) | CHRM4KDM4EPKM | |
| SCHEMBL22906774 | 0.83 | PRMT5 (0.44) | PRMT5WDR77KDM4EPKM | |
| SCHEMBL8478310 | 0.82 | GPR119 (0.57) | CHRM4ACHEBCHEPRMT5WDR77 | |
| SCHEMBL18497603 | 0.81 | KDM4E (0.57) | CHRM4ACHEBCHEKDM4EPKM | |
| SCHEMBL2246296 | 0.81 | GPR119 (0.54) | BCHEPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252613-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM, LLC (BM) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105717-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-08-27 | — | — | WO | disclosed |