Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104262 | 0.81 | GSK3B (0.53) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL26687976 | 0.81 | MAPK1 (0.57) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL18280919 | 0.80 | POLB (0.51) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL27858771 | 0.79 | PTPN1 (0.52) | ALDH1A1MAPTLMNAHTTTDP1 | |
| SCHEMBL26966709 | 0.77 | KMT2A (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL6782133 | 0.77 | NPC1 (0.53) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL105102 | 0.77 | GSK3B (0.55) | KMT2AMAPTMEN1LMNAPOLB | |
| SCHEMBL2867066 | 0.77 | GSK3B (0.67) | ALDH1A1MAPTLMNATDP1GSK3B | |
| SCHEMBL9386214 | 0.77 | GSK3B (0.55) | ALDH1A1KMT2AMAPTLMNAHTT | |
| SCHEMBL11604083 | 0.76 | RAB9A (0.54) | ALDH1A1KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924177-A | Preparation method of pazopanib intermediate 2, 3-dimethyl-6-amino-2H-indazole and analogues thereof | 南京杰运医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |