Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 7/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827719 | 0.81 | NPC1 (0.59) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL20528915 | 0.81 | GPR35 (0.38) | RAB9AKMT2APOLBLMNAMEN1 | |
| SCHEMBL8510583 | 0.81 | GPR35 (0.38) | RAB9AALDH1A1MAPTKMT2APOLB | |
| SCHEMBL22832993 | 0.74 | KMT2A (0.54) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL11802189 | 0.74 | ALDH1A1 (0.67) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL4008576 | 0.74 | ACP1 (0.59) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL31703305 | 0.73 | GPR35 (0.46) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL31703209 | 0.73 | GPR35 (0.46) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL3063974 | 0.72 | KMT2A (0.48) | MITFNPC1RAB9AXBP1NPSR1 | |
| SCHEMBL4006112 | 0.72 | ALDH1A1 (0.59) | MITFNPC1RAB9AXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117925757-A | Asparagine endopeptidase mediated polypeptide cyclization method and application thereof in phage display peptide library | 安徽大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117925757-A | Asparagine endopeptidase mediated polypeptide cyclization method and application thereof in phage display peptide library | 安徽大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117925758-A | Ligase-catalyzed polypeptide cyclization method and application thereof in phage display peptide library | 安徽大学 | 2024-04-26 | — | — | CN | disclosed |