Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957480 | 0.81 | POLB (0.40) | PTGS1PTGS2HPGDALDH1A1KDM4E | |
| SCHEMBL9988508 | 0.79 | EPHX1 (0.37) | — | |
| SCHEMBL14967733 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPT | |
| SCHEMBL27598745 | 0.73 | — | — | |
| SCHEMBL24015855 | 0.73 | ACACB (0.39) | — | |
| SCHEMBL4199271 | 0.73 | ADORA2A (0.36) | KMT2ASMN1; SMN2MEN1MAPTL3MBTL1 | |
| SCHEMBL2633391 | 0.71 | — | — | |
| SCHEMBL1646905 | 0.71 | — | — | |
| SCHEMBL28881697 | 0.71 | — | — | |
| SCHEMBL10572408 | 0.70 | ALDH1A1 (0.36) | PTGS1PTGS2KMT2AHPGDMT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |