SCHEMBL29202153

SCHEMBL29202153

COC(=O)c1ccc2c(c1)CCCN2.O=C(O)c1ccc2c(c1)CCCN2

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.78
MAPT P10636 3/20 0.78
GAA P10253 2/20 0.50
KDM6B O15054 1/20 0.47
KDM5C P41229 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
KDM2A Q9Y2K7 1/20 0.47
KDM3A Q9Y4C1 1/20 0.47
ALDH1A1 P00352 3/20 0.46
PLAU P00749 1/20 0.44
CRBN Q96SW2 1/20 0.43
PIR O00625 1/20 0.43
GSK3B P49841 1/20 0.43
HSF1 Q00613 1/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
ACHE P22303 2/20 0.42
PDK1 Q15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45146 0.94 MAPT (0.68) KDM4EMAPTGAAALDH1A1PLAU
SCHEMBL29995197 0.94 MAPT (0.68) KDM4EMAPTGAAALDH1A1PLAU
Hydrochloric Acid SCHEMBL1856980 0.93 MAPT (0.66) KDM4EMAPTGAAALDH1A1PLAU
Hydrochloric Acid SCHEMBL1264485 0.89 MAPT (0.60) KDM4EMAPTGAAALDH1A1PLAU
SCHEMBL45202 0.89 KDM4E (1.00) KDM4EMAPTGAAALDH1A1PLAU
SCHEMBL29673258 0.89 KDM4E (1.00) KDM4EMAPTGAAALDH1A1PLAU
SCHEMBL288320 0.86 MAPT (0.54) KDM4EMAPTGAAALDH1A1CRBN
SCHEMBL30445913 0.86 MAPT (0.54) KDM4EMAPTGAAALDH1A1CRBN
Hydrochloric Acid SCHEMBL699425 0.84 MAPT (0.53) KDM4EMAPTGAAALDH1A1CRBN
SCHEMBL30955089 0.83 MAPT (0.51) KDM4EMAPTGAAALDH1A1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115626889-B Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound 南京工业大学 2024-04-30 CN claimed
CN-115626889-B Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound 南京工业大学 2024-04-30 CN disclosed