Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554225 | 1.00 | MAPT (0.51) | MAPTKDM4EPPARGPPARDPPARA | |
| SCHEMBL29906783 | 0.91 | ALDH1A1 (0.47) | MAPTKDM4EGAAALDH1A1LMNA | |
| SCHEMBL2898350 | 0.91 | ALDH1A1 (0.47) | MAPTKDM4EGAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29940234 | 0.89 | ALDH1A1 (0.46) | MAPTKDM4EGAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3102567 | 0.89 | ALDH1A1 (0.46) | MAPTKDM4EGAAALDH1A1LMNA | |
| SCHEMBL29995197 | 0.88 | MAPT (0.68) | MAPTKDM4EGAAALDH1A1LMNA | |
| SCHEMBL45146 | 0.88 | MAPT (0.68) | MAPTKDM4EGAAALDH1A1LMNA | |
| SCHEMBL4601022 | 0.87 | NPC1 (0.51) | MAPTALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1856980 | 0.87 | MAPT (0.66) | MAPTKDM4EPPARGPPARDPPARA | |
| SCHEMBL29202153 | 0.83 | KDM4E (0.78) | MAPTKDM4EPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302184-B | 1,3, 4-Oxadiazolinone compounds and medicaments | 日本新药株式会社 | 2024-11-22 | — | — | CN | disclosed |
| CN-112543764-B | Amide compound with BET proteolytic induction effect and medical application thereof | 田边三菱制药株式会社 | 2024-05-10 | — | — | CN | disclosed |