Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202279 | 0.97 | PARP1 (0.66) | PARP1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29202261 | 0.88 | PARP1 (0.49) | PARP1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2515756 | 0.77 | MAPT (0.60) | KDM4EALDH1A1LMNAHPGDPTGES | |
| SCHEMBL29202288 | 0.77 | PARP1 (0.61) | PARP1KDM4EALDH1A1CHEK1HSD17B10 | |
| SCHEMBL16477971 | 0.75 | GABRP (0.61) | PARP1KDM4ELMNAHPGDCHEK1 | |
| SCHEMBL1869103 | 0.73 | MAPT (0.65) | KDM4EALDH1A1LMNAHPGDPTGES | |
| SCHEMBL29202281 | 0.73 | PARP1 (0.62) | PARP1KDM4EALDH1A1CHEK1HSD17B10 | |
| SCHEMBL29022540 | 0.73 | CHEK1 (0.56) | KDM4EALDH1A1HPGDCHEK1HSD17B10 | |
| SCHEMBL15202003 | 0.73 | MAPT (0.61) | PARP1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29202275 | 0.72 | CDK2 (0.43) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964626-A | Method for preparing indole [3,2-a ] carbazole alkaloid by taking 2, 3' -biindole as raw material | 重庆医科大学 | 2024-05-03 | — | — | CN | disclosed |