Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297864 | 0.79 | CYP11B1 (0.47) | NUDT1CYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL3138561 | 0.77 | CYP2A6 (0.50) | NUDT1CYP11B1CYP11B2HTTCYP3A4 | |
| SCHEMBL30338495 | 0.77 | CYP2A6 (0.50) | NUDT1CYP11B1CYP11B2HTTCYP3A4 | |
| SCHEMBL233227 | 0.73 | MKNK1 (0.53) | NUDT1PRKD3PRKCGPRKCBLCK | |
| SCHEMBL7953757 | 0.72 | CFTR (0.46) | CFTRCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL4380382 | 0.72 | DYRK1A (0.39) | LCKHTTEGFR | |
| SCHEMBL31356506 | 0.71 | CYP1A2 (0.49) | HTTCYP3A4ALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL27503313 | 0.71 | CYP17A1 (0.60) | CYP11B1CYP11B2CYP17A1CYP19A1POLB | |
| SCHEMBL5457794 | 0.71 | POLB (0.55) | CYP11B1CYP11B2CYP17A1CYP19A1POLB | |
| SCHEMBL4381004 | 0.70 | SMN1; SMN2 (0.41) | LCKHTTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |