Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 3/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.39 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.39 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.39 |
| ▸ | TXK | P42681 | 1/20 | 0.39 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.39 |
| ▸ | STK16 | O75716 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11916045 | 0.82 | FGFR2 (0.38) | SMN1; SMN2RUNX1GAKRIPK2NLK | |
| SCHEMBL4380382 | 0.79 | DYRK1A (0.39) | TSHRDYRK1AGAAHPGDGAK | |
| SCHEMBL29813440 | 0.79 | DYRK1A (0.39) | TSHRDYRK1AGAAHPGDGAK | |
| SCHEMBL23148039 | 0.79 | DYRK1A (0.39) | SMN1; SMN2TSHRDYRK1AGAAHPGD | |
| SCHEMBL28026404 | 0.79 | HTT (0.44) | DYRK1AGAAHPGDGAKRIPK2 | |
| SCHEMBL29954197 | 0.77 | DYRK1A (0.38) | TSHRDYRK1AGAAHPGDGAK | |
| SCHEMBL31214552 | 0.75 | DYRK1A (0.37) | SMN1; SMN2TSHRDYRK1AHTTHSD17B10 | |
| SCHEMBL31214523 | 0.75 | DYRK1A (0.37) | SMN1; SMN2TSHRDYRK1AHPGDHTT | |
| SCHEMBL4372362 | 0.74 | TSHR (0.44) | SMN1; SMN2TSHRDYRK1AHTTHSD17B10 | |
| SCHEMBL25405415 | 0.74 | LMNA (0.43) | DYRK1AGAAHTTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |