Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279374 | 0.95 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| Hydrochloric Acid SCHEMBL29204567 | 0.85 | DHODH (0.36) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL5593172 | 0.81 | MAPT (0.45) | PDE4DPDE4APDE4BPDE4CHPGD | |
| Hydrochloric Acid SCHEMBL29204594 | 0.80 | PDE4D (0.49) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL19090202 | 0.80 | PTPN11 (0.36) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL15521503 | 0.80 | PDE4B (0.33) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL15521501 | 0.80 | GRM2 (0.36) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL15521504 | 0.80 | NOS3 (0.35) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL19066435 | 0.79 | HDAC1 (0.42) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL17037213 | 0.79 | HDAC1 (0.39) | PDE4DPDE4APDE4BPDE4CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |