Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279374 | 0.85 | PDE4D (0.36) | MAPTTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL4284397 | 0.82 | TSHR (0.44) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL4278364 | 0.82 | TSHR (0.44) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL29204573 | 0.81 | PDE4D (0.34) | MAPTTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL28238622 | 0.80 | KDM4E (0.43) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29204567 | 0.79 | DHODH (0.36) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL19066414 | 0.78 | KDM4E (0.43) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL4280199 | 0.78 | TSHR (0.41) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL17037229 | 0.78 | TSHR (0.41) | MAPTHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL17037230 | 0.78 | TSHR (0.41) | MAPTHSD17B10TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |